Longitudinal Analysis of Substance Use Disorder Symptom Severity at Age 18 Years and Substance Use Disorder in Adulthood, in JAMA Network Open
key takeaway: "In this national multicohort study of 5317 individuals followed from ages 18 to 50 years, the majority of adolescents with the most severe SUD symptoms had 2 or more SUD symptoms in adulthood. Most adults using prescribed opioids, sedatives, or tranquilizers had multiple SUD symptoms during adolescence."
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