Ketamine Infusions and Rapid Reduction of Suicidal and Depressive Symptoms in Major Depressive Episode: A Systematic Review and Meta-Analysis
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Ketamine Infusions and Rapid Reduction of Suicidal and Depressive Symptoms in Major Depressive Episode: A Systematic Review and Meta-Analysis, in JAMA Psychiatry
key takeaway: "This systematic review and meta-analysis of 26 randomized clinical trials with 1166 patients with an MDE found that ketamine was efficacious in reducing suicidal and depressive symptoms rapidly, within hours. Reported serious adverse events (eg, deaths) were unrelated to the interventions, and other adverse events (eg, headache) were transient and resolved during the trials."

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