A Systematic Review of the Relationship between Social Isolation and Physical Health in Adults, in Healthcare
key takeaway: "Social isolation is related to increases in inflammatory biomarkers associated with diseases, all-cause mortality, lower expectations of longevity, and frailty. In addition, social isolation was associated with cognitive decline and disruptions in sleep. Poor oral health increased social isolation. The results further indicated that decreased physical performance/function and a decline in physical activity were associated with social isolation, as well as decreased overall physical health, poor health behaviors, and self-care, and decreased health-related quality of life."
Social Isolation and Loneliness in Older Adults, by JAMA (patient page)
Social Isolation and Loneliness Outreach Toolkit, by the National Institute on Aging