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key takeaway: "In 2022, the prevalence of feeling lonely always, usually, or sometimes among adults in 26 U.S. states was highest for bisexual (56.7%) and transgender persons (range = 56.4%–63.9%); these groups also reported the highest prevalence of stress, frequent mental distress, and history of depression (range = 34.3%–67.2%). Prevalence of lack of social and emotional support was elevated among transgender adults."

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